The best road trip stops on the Tallahassee to New Orleans drive are Pensacola FL, Mobile AL and Biloxi MS. The distance from Tallahassee to New Orleans by car is 387 miles, with a 5h36m driving time.
Planning a Tallahassee to New Orleans road trip itinerary
The Tallahassee to New Orleans drive takes you from Florida’s capital to the most intoxicating city in Louisiana.
Top Tallahassee experiences include the Museum of Florida History, which tells the tale of the Sunshine State. That covers everything from prehistoric mastodons to the Spanish conquest and Disney.
The Tallahassee Museum, meanwhile, flits all over the place, from sculpture to birds of prey. For natural beauty, head to the Alfred B Maclay Gardens State Park.
Good Tallahassee accommodation options include the hip Aloft Tallahassee Downtown and the often great value Four Points by Sheraton.
5 great experiences in New Orleans to book today
- 🎷 Steamboat Natchez jazz cruise – Go for a jazz cruise aboard the Steamboat Natchez.
- 🍤 French Quarter food tour – Take a French Quarter food tour and discover Louisiana’s distinctive Cajun and Creole cuisine.
- 🐊 Swamp and bayou boat tour – Enjoy a swamp and bayou boat tour with a quieter boat for better wildlife sightings.
- 👻 New Orleans’ dark side – On a tour of New Orleans’ dark side, uncover ghosts, vampires, crime and voodoo.
- 🏛️ Whitney Plantation tour – Hear the true stories of slavery on a Whitney Plantation tour with transport from New Orleans.
New Orleans resolutely refuses to feel like any other American city. From the raucous hedonism of Bourbon Street to the European-influenced charm of the French Quarter, New Orleans is mesmerizingly unusual to hang out in.
Those wanting to explore the city’s heritage can visit historic home museums, such as the BK House, Gallier House and Hermann-Grima House. The Cabildo, St Louis Cathedral and Old Ursuline Convent also ooze historic grandeur.
Big hitter attractions include the World War II Museum and Audubon Zoo, but there’s a more distinctively NOLA flavour at Mardi Gras World and the New Orleans Jazz Museum.
Top New Orleans experiences include French Quarter food tours, haunted pub crawls, jazz cruises aboard the steamboat Natchez and cemetery walking tours.
Tallahassee to New Orleans distance and driving time
By car, the distance from Tallahassee to New Orleans is 387 miles. This makes for a driving time of around five hours and 36 minutes. The bulk of the drive is along the I-10.
The best stops on the Tallahassee to New Orleans road trip are Pensacola FL, Mobile AL and Biloxi MS.
Tallahassee to New Orleans road trip attractions: Pensacola FL
5 top experiences to book in Pensacola
- 🐬 Meet the local dolphins on a cruise aboard the Frisky Mermaid.
- 🌅 Take an afternoon tiki boat cruise – and see the spectacular sunset.
- 👻 Learn about perdition, pirates and purgatory on a Pensacola ghost tour.
- 🍴 Feast on a food tour down Pensacola’s legendary Palafox Street.
- 🚌 Explore Pensacola’s highlights on a hop-on, hop-off bus tour.
The westernmost city on the Florida Panhandle, Pensacola is home to a major US Naval Station. You can visit the National Naval Aviation Museum and the Pensacola Lighthouse. Elsewhere, Historic Pensacola Village brings together heritage buildings, Gulf Breeze Zoo keeps the kids happy and Fort Pickens looks out towards Big Lagoon State Park.
But for most visitors, interest will lie in the white sand beaches and barrier islands.
Top Pensacola activities include nighttime kayaking with colourful LEDs lighting up the kayaks, and dolphin-watching cruises around the bay.
Other ways of exploring include downtown food tours, ghost and graveyard tours, guided pub crawls, Segway tours and sunset cruises.
For beachside Pensacola accommodation with great guest reviews, take a look at the Pensacola Beach Resort and the SpringHill Suites Pensacola Beach.
Tallahassee to New Orleans drive: Mobile AL
The Alabama Gulf Coast port city of Mobile has a perhaps unexpected party spirit. This is best explored in the bars, or at the Mobile Carnival Museum.
You can also head on board the USS Alabama battleship or visit the National Maritime Museum of the Gulf. The latter includes a ship simulator, where you can have a go at steering a ship through the Gulf.
Elsewhere, Colonial Fort Conde is the top historic attraction and the Exploreum Science Center has plenty of button-pushing for kids.
Mobile experience options include a downtown food tour and a cruise around the port.
Top Mobile accommodation picks include the personality-packed Fort Conde Inn and the riverside Renaissance Mobile Riverview Plaza.
Best stops between Tallahassee and New Orleans: Biloxi MS
Biloxi on the Mississippi coast is best known as a casino destination, but there’s plenty to keep non-gamblers interested. The Biloxi Lighthouse opened in 1848, and is now open for public tours. The Maritime and Seafood Industry Museum covers the region’s history, and looks at just how big a business fishing is. You can also take a cruise on one of the schooners moored outside the museum.
Also in Biloxi is Beauvoir, the lavish home of Confederate president Jefferson Davis. The mansion is open for tours.
For Biloxi accommodation, try the Scarlet Pearl Casino Resort for entertainment and the South Beach Hotel and Suites for beachside location.
More Florida and Louisiana road trips
- The distance, driving time and best stops on a Jacksonville to Tallahassee drive.
- What to see on the Tallahassee to Mobile drive.
- Getting to Pensacola: The best stops on the Atlanta to Pensacola drive, Birmingham to Pensacola drive, Jacksonville to Pensacola drive, Mobile to Pensacola drive and Tallahassee to Pensacola drive.
- Getting to New Orleans: The best stops on the Atlanta to New Orleans drive.
- Where to stop on the Atlanta to Baton Rouge drive, Austin to Baton Rouge drive, Dallas to Baton Rouge drive and Houston to Baton Rouge drive.